2023<\/p>\n\n\n\n
Kouno T, Zeng S, Wang Y, Duan Y, Lang S, Gao B, Hartmann P, Cabr\u00e9 N, Llorente C, Galbert C, Emond P, Sokol H, James M, Chao CC, Gao JR, Perreault M, Hava DL, Schnabl B. Engineered bacteria producing aryl-hydrocarbon receptor agonists protect against ethanol-induced liver disease in mice. Alcohol Clin Exp Res.<\/strong> 2023 Mar 5. doi: 10.1111\/acer.15048.<\/p>\n\n\n\n Moreau C , El Habnouni C, Lecron J-C, Morel F, Delwail A, Le Gall-Ianotto C, Le Garrec R, Misery L, Piver E, Vaillant L, Lefevre A, Emond P, Blasco H, Samimi M. Investigation of pathophysiological pathways in Burning Mouth Syndrome by comparative salivary analysis of the global metabolome, pro-inflammatory cytokines, steroids and markers of neurogenic inflammation: a prospective case-control study. 2022 Pain<\/strong> 164(3):e144-e156.<\/p>\n\n\n\n Kerneis S, Escoffre JM, Galvin JJ 3rd, Bouakaz A, Presset A, Alix C, Oujagir E, Lef\u00e8vre A, Emond P, Blasco H, Bakhos D. Sonoporation of the Round Window Membrane on a Sheep Model: A Safety Study. Pharmaceutics<\/strong> 2023 Jan 29;15(2):442.<\/p>\n\n\n\n M Ghiboub, R Sigall Boneh, B Sovran, E Wine, A Lef\u00e8vre, P Emond, C M Verburgt, M A Benninga, W J de Jonge, J E Van Limbergen. Sustained Diet-Induced Remission in Pediatric Crohn\u2019s Disease Is Associated With Kynurenine and Serotonin Pathways.<\/strong> Inflammatory Bowel Diseases<\/strong> 2023 https:\/\/doi.org\/10.1093\/ibd\/izac262<\/a><\/p>\n\n\n\n 2022<\/p>\n\n\n\n Catanese S, Khanna RK , Lefevre A , Alarcan H , Pisella PJ , Emond P, H\u00e9l\u00e8ne Blasco. Validation of metabolomic and lipidomic analyses of human tears using ultra-high-performance liquid chromatography tandem mass spectrometry. 2022 Talanta<\/strong> 243:123932<\/p>\n\n\n\n Khanna RK, Catenese S, Emond P, Corcia P, Blasco H, Pisella PJ. Metabolomics and lipidomics approaches in human tears: A systematic review. Survey of Ophthalmology<\/strong> 2022, 67, 4, 1229<\/p>\n\n\n\n Gu\u00e9guinou M, Ibrahim S, Bourgeais J, Robert A, Pathak T, Zhang X, Crott\u00e8s D, Dupuy J, Ternant D, Monbet V, Guibon R, Flores\u2010Romero H, Lef\u00e8vre A, Lerondel S, Le Pape A, Dumas JF, Frank P, Girault A, Chautard R, Gu\u00e9raud F, Garc\u00eda\u2010S\u00e1ez A, Ouaissi M, Emond P, Sire O, H\u00e9rault O, Fromont\u2010Hankard G, Vandier C, Tougeron D, Trebak M, Raoul W, Lecomte T. Curcumin and NCLX inhibitors share anti\u2010tumoral mechanisms in microsatellite\u2010instability\u2010driven colorectal cancer 2022 Cellular and Molecular Life Sciences<\/strong> 79:284, https:\/\/doi.org\/10.1007\/s00018-022-04311-4 <\/p>\n\n\n\n Lanznaster D, Bruno C, Bourgeais J, Emond P, Zemmoura I, Lefevre A, Reynier P, Eymieux S, Blanchard E, Vourc\u2019h P, Andres C, Bakkouche S, Herault O, Favard L, Corcia P, Blasco H. Metabolic Profile and Pathological Alterations in the Muscle of Patients with Early-Stage Amyotrophic Lateral Sclerosis. 2022 Biomedicines<\/strong> Accepted<\/p>\n\n\n\n Boullaud L, Blasco H, Cabillaud E, Emond P, Bakhos D. Immediate-Early Modifications to the Metabolomic Profile of the Perilymph Following an Acoustic Trauma in a Sheep Model. Journal of Clinical Medicine<\/strong> 2022, 11, 16, 4668. (IF=4,964).<\/p>\n\n\n\n Modoux M, Rolhiona N, Lefevre J, Oeuvray C, N\u00e1dvorn\u00edk P, Illes P, Emond P, Parc Y, Mani S, Dvorak Z, Sokol H. Butyrate acts through HDAC inhibition to enhance aryl hydrocarbon receptor activation by gut microbiota-derived ligands. 2022 Gut Microbes<\/strong> – https:\/\/doi-org.proxy.insermbiblio.inist.fr\/10.1080\/19490976.2022.2105637<\/p>\n\n\n\n Beauclercq S, Mignon-Grasteau S, Petit A, Berger Q, Lefevre A, Metay-Coustard S, Tesseraud S, Emond P, Berri C, Le Bihan-Duval E. A divergent selection on breast meat ultimate pH, a key factor for chicken meat quality, is associated with different circulating lipid profiles. 2022 Frontiers in Physiology<\/strong> 13, 935868<\/p>\n\n\n\n Pochon C, Perouf R, Bertrand A, Notarantonio A-B, Charif N, De Carvalho Bittencourt M, Fouquet G, Cauchois G, Voisin C, Bensoussan D, Emond P, Sartelet H, Moulin D, De Isla N, D\u2019avens M, Rubio M T. IFN-\u03b3 Primed Wharton’s Jelly Mesenchymal Stromal Cells Inhibit T Cell Proliferation By Synergistic IDO and Mitochondrial Transfer Mechanisms 2022 Blood<\/strong> 140 (Supplement 1): 4504\u20134505<\/p>\n\n\n\n N. Baroukh, N. Canteleux, A. Lef\u00e8vre, C. Dupuy, C. Martias, A. Presset, M. Subramaniam, JR. Hawse, P. Emond, P. Pouletaut, S. Morandat, S.F. Bensamoun, L. Nadal-Desbarats. Serum and soleus metabolomics signature of Klf10 knockout mice to identify potential biomarkers. Metabolites 2022<\/strong>.<\/p>\n\n\n\n M. Kammoun, L. Nadal-Desbarats, S. M\u00eame, A. Lafoux, C. Huchet, G. Meyer-Dilhet, J. Courchet, F. Montigny, F. Szeremeta, W. M\u00eame, V. Veksler, J. Piquereau, P. Pouletaut, M. Subramaniam, J.R. Hawse, JM. Constans, S. F. Bensamoun. Klf10 as a mitochondrial regulator in the cerebellum. Journal of Biomedical Sciences and Engineering 2022<\/strong>.<\/p>\n\n\n\n A. Presset, S. Bodard, A. Lef\u00e8vre, A. Millet, E. Oujagir, C. Dupuy, T. Iazour\u00e8ne, A. Bouakaz, P. Emond, JM. Escoffre, L. Nadal-Desbarats. First metabolomic signature of blood brain barrier opening induced by microbubble-assisted ultrasound. Frontier in Molecular Neurosciences, 2022<\/strong>.<\/p>\n\n\n\n A. Guillon, D. Br\u00e9a-Diakite, A.Cezard, T. Baranek, J.Bourgeais, F Picou, V. Vasseur, J.M. Carballido, L. Nadal Desbarats, F. Dingli, A. Turtoi, A. Le Gouellec, F. Fauvelle, T. Cr\u00e9pin, P.S. Hiemstra, C. Paget, D. Loew, O. Herault, N. Naffakh, R. Le Goffic and M. Si-Tahar. Host succinate inhibits influenza virus infection through succinylation and nuclear retention of the viral nucleoprotein. The EMBO Journal 2022.<\/strong><\/p>\n\n\n\n Q. Faucher, H. Alarcan, FL. Sauvage, L. Forestier, E. Miquelestorena-Standley, L. Nadal-Desbarats, H. Arnion, JC. Venhard, N. Brichart, F. Bruy\u00e8re, P. Marquet, and C. Barin-Le Guellec. Perfusate metabolomics content and expression of tubular transporters during Human kidney graft preservation by hypothermic machine perfusion. Transplantion 2022<\/strong>.<\/p>\n\n\n\n S. M\u00e9tayer-Coustard, A. Petit, S. R\u00e9hault-Godbert, L. Nadal-Desbarats, E. Cailleau-Audouin, P. Chartrin, E. Raynaud, J. Jimenez, S. Tesseraud, C. Berri, E. Le Bihan-DuvalNutrient sources differ in the fertilised eggs of two divergent broiler lines selected for meat ultimate pH. Scientific Reports 2022<\/strong>.<\/p>\n\n\n\n 2021<\/p>\n\n\n\n Goudet G, Prunier A, Nadal-Desbarats L, Grivault D, Ferchaud S, Pianos A, Haddad L, Montigny F, Douet C, Savoie J, Maupertuis F, Roinsard A, Boulot S, Liere P. Steroidome and metabolome analysis in gilt saliva to identify potential biomarkers of boar effect receptivity. Animal, 2021 Fev https:\/\/doi.org\/10.1016\/j.animal.2020.100095<\/a><\/p>\n\n\n\n Calderari S, Daniel N, Mourier E, Richard C, Dahirel M, Lager F, Marchiolm C, Renault G, Gatien J, Nadal-Desbarats L, Chavatte-Palmer P, Duranthon V. Metabolomic differences in blastocoel and uterine fluids collected in vivo by ultrasound biomicroscopy on rabbit embryos. Biology of reproduction. 2021 Jan.<\/p>\n\n\n\n Fatet A., Nadal-Desbarats L., Boissard K., Antar C., Freret S., Pellicer-Rhttps:\/\/metabolomique.med.univ-tours.fr\/wp-admin\/post-new.php?post_type=pageubio MT., Monniaux D., Goudet G. Characterization of serum metabolome changes during the 5 weeks prior to breeding in female goat kids. Livestock Science. Available online 29 May 2021, 104572.<\/p>\n\n\n\n Dupuy C, Castelnau P, Mavel S, Lefevre A, Nadal-Desbarats L, Bodars S, Busson J, Dufour-Rainfray D, Blasco H, Emond P, Galineau L. SHR\/NCrl rats as a model of ADHD can be discriminated from controls based on their brain, blood or urine metabolomes. Translational Psychiatry 2021 accepted<\/p>\n\n\n\n Janati Idrissi S, Le Bourhis D, Lefevre A, Emond P, Le Berre L, Desnoes O, Joly T, Buff S, Maillard V, Schibler L, Salvetti P, Elis S.Lipid profile of bovine grade-1 blastocysts produced either in vivo or in vitro before and after slow freezing process. Scientific Reports 2021 11:11618, 10.1038\/s41598-021-90870-8<\/p>\n\n\n\n JanatiIdrissi S, Le Bourhis S, Lefevre A, Emond P, Le Berre L, Desnoes O, Joly T, Buff S, Ferret S, Schibler L, Salvetti P, Elis S. Effects of the donor factors and freezing protocols on the bovine embryonic lipid profile. 2021 Biology of Reproduction, ioab198, https:\/\/doi.org\/10.1093\/biolre\/ioab198.<\/p>\n\n\n\n Alarcan H, Chaumond R, Emond P, Benz De Bretagne I, Lefevre A, Bakkouche S, Veyrat-Durebex C, Vourc\u2019h P, Andres C, Corcia P, Blasco H. Some Csf Kynurenine Pathway Intermediates Associated With Disease Evolution In Amyotrophic Lateral Sclerosis. Biomolecules 2021 11, 691<\/p>\n\n\n\n Bourdin-Pintueles A, Galineau L, Nadal-Desbarats L, Dupuy C, Bodard S, Busson J, Lefevre A, Emond P, Mavel S (2021) Maternal Rat Metabolomics: Amniotic Fluid and Placental Metabolic Profiling Workflows, J. Prot. Res., 20:3853-3864, Q1, 10.1021\/acs.jproteome.1c00145<\/p>\n\n\n\n Martias C, Baroukh N, Mavel S, Blasco H, Lef\u00e8vre A, Roch L, Montigny F, Gatien J, Schibler L, Dufour-Rainfray D, Nadal-Desbarats L, Emond P (2021) Optimization of Sample Preparation for Metabolomics Exploration of Urine, Feces, Blood and Saliva in Humans Using Combined NMR and UHPLC-HRMS Platforms. Molecules, in press, Q2, 10.3390\/molecules26144111<\/p>\n\n\n\n Delaby C, Teunissen CE, Blennow K, Alcolea D, Arisi I, Amar EB, Beaume A, Bedel A, Bellomo G, Bigot-Corbel E, Bjerke M, Blanc-Quintin MC, Boada M, Bousiges O, Chapman MD, DeMarco ML, D’Onofrio M, Dumurgier J, Dufour-Rainfray D, Engelborghs S, Esselmann H, Fogli A, Gabelle A, Galloni E, Gondolf C, Grandhomme F, Grau-Rivera O, Hart M, Ikeuchi T, Jeromin A, Kasuga K, Keshavan A, Khalil M, Kortvelyessy P, Kulczynska-Przybik A, Laplanche JL, Lewczuk P, Li QX, Lleo A, Malaplate C, Marquie M, Masters CL, Mroczko B, Nogueira L, Orellana A, Otto M, Oudart JB, Paquet C, Paoletti FP, Parnetti L, Perret-Liaudet A, Peoc’h K, Poesen K, Puig-Pijoan A, Quadrio I, Quillard-Muraine M, Rucheton B, Schraen S, Schott JM, Shaw LM, Suarez-Calvet M, Tsolaki M, Tumani H, Udeh-Momoh CT, Vaudran L, Verbeek MM, Verde F, Vermunt L, Vogelgsang J, Wiltfang J, Zetterberg H, Lehmann S (2021) Clinical reporting following the quantification of cerebrospinal fluid biomarkers in Alzheimer’s disease: An international overview. Alzheimers & Dementia, Q1, 10.1002\/alz.12545<\/p>\n\n\n\n Martias C, Gatien J, Roch L, Baroukh N, Mavel S, Lef\u00e8vre A, Montigny F, Schibler L, Emond P, Nadal-Desbarats L. Analytical Methodology for a Metabolome Atlas of Goat’s Plasma, Milk and Feces Using 1 H-NMR and UHPLC-HRMS. Metabolites. 2021 Oct 4;11(10):681, Q2, 10.3390\/metabo11100681<\/p>\n\n\n\n Veyrat-Durebex C, Benz-de Bretagne I, Clavier V, Bruno C, Andres C.R, Antar C, Hennart B, Maillot F, Nadal-Desbarats L, Blasco H (2021) Quality consideration for the validation of urine TMA and TMAO measurement by Nuclear Magnetic Resonance spectroscopy in Fish Odor Syndrome. Anal. Biochem., in press, 10.1016\/j.ab.2021.114330<\/p>\n\n\n\n Altin\u00e9-Samey R, Antier D, Mavel S, Dufour-Rainfray D, Balageas AC, Beaufils E, Emond P, Foucault-Fruchard L, Chalon S (2021) The contributions of metabolomics in the discovery of new therapeutic targets in Alzheimer’s disease. Fundam. Clin. Pharmacol., in press, 10.1111\/fcp.12654<\/p>\n\n\n\n Trinh TT, Blasco H, Maillot F, Bakhos D (2021) Hearing loss in inherited metabolic disorders: A systematic review. Metabolism, 122:154841, Q1, 10.1016\/j.metabol.2021.154841<\/p>\n\n\n\n D Sedda, C Mackowiak, J Pailloux, Culerier, A Dudas, P Rontani, N Erard, A Lefevre, S Mavel, P Emond, F Foucher, M Le Bert, V FJ Quesniaux, M J. Mihatsch, B Ryffel, M Erard-Garcia. Deletion of Mocos induces xanthinuria with obstructive nephropathy and major metabolic disorders in mice. Kidney360 2021<\/p>\n\n\n\n 2020<\/p>\n\n\n\n Presset A., <\/sup>Bonneau C., Kazuyoshi S., Nadal-Desbarats L., Mitsuyoshi T., <\/sup>Bouakaz A., Nobuki K., Escoffre JM., Sasaki N. Endothelial Cells, First Target Of Drug Delivery Using Microbubble-Assisted Ultrasound. Ultrasound In Medicine And Biology. 2020<\/p>\n\n\n\n Dufour-Rainfray<\/a> <\/sup>D., Lamb\u00e9rioux<\/a> <\/sup>M., <\/sup>Boulard<\/a> P., <\/sup>Guidotti<\/a> M., <\/sup>Delaye<\/a> JB., <\/sup>Ribeiro<\/a> MJ., <\/sup>Gauchez<\/a> <\/sup>AS.,Balageas<\/a> AC., <\/sup>Emond<\/a> P., <\/sup>Agin<\/a> A.. Metabolomics \u2013 an overview. From basic principles to potential biomarkers (part 2) M\u00e9tabolomique \u2013 un aper\u00e7u. Des principes de base aux biomarqueurs potentiels (2e<\/sup> partie). M\u00e9decine Nucl\u00e9aire<\/a>. Available online 16 March 2020<\/p>\n\n\n\n Wartenberg M., Andrault P-M, Saidi A., Nadal-Desbarats L., Lecaille F., Lalmanach G.. Oxidation Of Cathepsin S By Major Chemicals Of Cigarette Smoke. Free Radical Biology And Medecine 2020 Feb 19; 150:53-65<\/p>\n\n\n\n Lanznaster D., Hergesheimer R., Bakkouche S., Beltran S., Vourc\u2019h P., Andres C., Dufour-Rainfray D., Corcia P., Blasco H.. 1-42 And Tau As Potential Biomarkers For Diagnosis And Prognosis Of Amyotrophic Lateral Sclerosis. Int. J. Mol. Sci. 2020 21, 2911; Doi:10.3390\/Ijms21082911 <\/p>\n\n\n\n Gonzales B., De Rocquigny H., Beziau A., Durand S., Burlaud-Gaillard J., Lefevre A., Krull S., Emond P., Brand D., Piver E.. Type I Phosphatidylinositol-4-Phosphate 5-Kinase \u0391 And \u0393 Play A Key Role In Targeting Hiv-1 Pr55gag <\/sup>To The Plasma Membrane. Journal Of Virology 2020 <\/p>\n\n\n\n Kammoun M., Veksler V., Nadal-Desbarats L., Meme S., Piquereau J., Holte M. H. N., J Constans J-M., Najafova Z., Subramaniam M., Johnsen S., Hawse J-R., Bensamoun s f ;. Novel role of Tieg1 in muscle metabolism and mitochondrial oxidative capacities. Acta physiologica 2019 (Sep 27<\/p>\n\n\n\n Gonzales B, De Rocquiny H, Beziau A, Durand S, Burlaud J, Lefevre A, Krull S, Emond P, Brand D, Piver E. Type I phosphatidylinositol-4-phosphate 5-kinase \u03b1 and \u03b3 play a key role in targeting HIV-1 Pr55Gag <\/sup>to the plasma membrane. Journal of Virology 2020, 94,14, N\u00b0e00189-20 <\/p>\n\n\n\n Dufour-Rainfray D, Lamberioux M, Boulard P, Guidotti M, Delaye Jb, Ribeiro Mj, Gauchez As, Balageas Ac, Emond P, Agin A. Metabolomics – an overview. From basic principles to potential biomarkers. Medecine Nucleaire – Imagerie Fonctionnelle et M\u00e9tabolique 2020, 44, 3, 158-163<\/a><\/p>\n\n\n\n Wrzosek L, Ciocan D, Hugot C, Spatz <\/sup>M, <\/sup>Dupeux M, Houron C, Li\u00e9vin-Le Moal V, Puchois V, Ferrere G, Trainel N Mercier-Nom\u00e9 F, Durand S, Enot D, Kroemer G, Voican C, Emond P, Straube M, Sokol H, Perlemuter G, Cassard A-M. Microbiota tryptophan metabolism induces aryl hydrocarbon receptor activation and improves alcohol-induced liver injury. Gut 2020, 0:1-10, doi:10.1136\/gutjnl-2020-321565 <\/p>\n\n\n\n Delaye Jb, Lanznater D, Veyrat-Durebex C, Lefevre A, Hergesheimer R, Lecron Jc, Vourc\u2019h P, Andres Cr, Corcia P, Emond P, Blasco H. Behavioural, hormonal, inflammatory and metabolic effects associated with FGF21 pathway activation in an ALS mouse model. Neurotherapeutics 2020 DOI: 10.1007\/s13311-020-00933-3 <\/p>\n\n\n\n Blasco H, Bessy C, Plantier L, Lefevre A, Piver E, Bernard L, Marlet J, Benz-De-Bretagne I, Cannet P, Lumbu H, Morel T, Boulard P, Andres Cr, Vourc\u2019h P, Guillon A, Emond P. The specific metabolome profiling of patients infected by SARS-COV-2 supports the key role of tryptophan-nicotinamide pathway and cytosine metabolism. Scientific Reports 2020 10, 1, 16824<\/a><\/p>\n\n\n\n 2019<\/p>\n\n\n\n Vetel S., Serriere S., Vercouillie J., Vergote J., Chicheri G., Deloye J-B., Dolle F., Bodard S., Tronel C., Nadal-Desbarats L., Lefevre A., Emond P., Chalon S. Extensive Exploration Of A Novel Rat Model Of Parkinson’s Disease Using Partial 6-Hydroxydopamine Lesion Of Dopaminergic Neurons Suggests New Therapeutic Approaches. Synapse 2019 Mar;73(3):e22077. doi: 10.1002\/syn.22077.<\/p>\n\n\n\n Lefevre A., Mavel S., Nadal-Desbarats L., Galineau L., Attucci S., Dufour D., Sokol H., Emond P. Validation Of Global Quantitative Analysis Of Tryptophan Metabolites In Mice Using Lc-Hrms. Talanta. 2019;195:593-598. doi: 10.1016\/j.talanta.2018.11.094. <\/p>\n\n\n\n Beauclercq S, Lefevre A, Montigny F, Collin A, Tesseraud S, Leterrier C, Emond P, Guilloteau L. A Multiplatform Metabolomic Approach To Characterize Fecal Signatures Of Negative Postnatal Events In Chicks: A Pilot Study. Journal Of Animal Science And Biotechnology. 2019 Apr 9;10:21 <\/p>\n\n\n\n Goudet G., Nadal-Desbarats L., Douet C., Savoie J., Staub C., Venturi E., Ferchaud S., Boulot S., Prunier A. Salivary And Urinary Metabolome Analysis For Pre-Puberty-Related Biomarkers Identification In Porcine. Animal. 2019 Apr 13(4):760-770<\/p>\n\n\n\n Beauclerc S., Lefevre A., Nadal-Desbarats L., Germain K., Praud C., Emond P., Bihan-Duval EL., Mignon-Grasteau S. Does Lipidomic Serum Analysis Support The Assessment Of Digestive Efficiency In Chickens? Poult Sci.<\/a> 2019 98, 3, 1425-1431<\/p>\n\n\n\n Hendrikx T., Duan Y., Wang Y., Oh J-H., Alexander L M., Huang W., Emond P., Sokol H., Van Pijkeren J P., Schnabl B. Bacteria Engineered To Produce Il22 In Intestine Induce Expression Of Reg3g To Reduce Ethanol-Induced Liver Disease In Mice\u00a0\u00bb Has Been Successfully Submitted Online And Is Presently Being Given Full Consideration For Publication In Gut. Gut 2019 68, 8, 1504-1515. <\/p>\n\n\n\n Trinh T-T., Blasco H., Emond P., Andres C., Lefevre A., Lescanne E., Bakhos D. Relationship Between Metabolomics Profile Of Perilymph In Cochlear-Implanted Patients And Duration Of Hearing Loss. Metabolites 2019 , 9, 262 <\/p>\n\n\n\n Kammoun M., Veksler V., Nadal-Desbarats L., Meme S., Piquereau J., Holte M. H. N., Constans J-M, Najafova Z., Subramaniam M., Johnsen S., Hawse J-R., Bensamoun S F. Novel Role Of Tieg1 In Muscle Metabolism And Mitochondrial Oxidative Capacities. Acta Physiologica 2019 (Sep 27<\/p>\n\n\n\n Tardieu A., Chazelas P., Faye P-A., Favreau F., Nadal-Desbarats L., Sallee C., Couquet C-Y., Marquet P., Barin-Le Guellec C. Changes In The Metabolic Composition Of Storage Solution With Prolonged Cold Ischemia Of The Uterus. J. Assisted Reproduction And Genetics. 2019 36:1169-1178. <\/p>\n\n\n\n Beauclerc S, Lefevre A, Nadal-Desbarats L, Germain K, Praud C, Emond P, Bihan-Duval El, Mignon-Grasteau S. Does lipidomic serum analysis support the assessment of digestive efficiency in chickens? Poult Sci.<\/a> 2019 98, 3, 1425-1431<\/a>. <\/p>\n\n\n\n Vetel S, Serriere S, Vercouillie J, Vergote J, Chicheri G, Deloye J-B, Dolle F, Bodard S, Tronel C, Nadal-Desbarats L, Lefevre A, Emond P, Chalon S; Extensive exploration of a novel rat model of Parkinson’s disease using partial 6-hydroxydopamine lesion of dopaminergic neurons suggests new therapeutic approaches. Synapse 2019 76, 3, (IF= 2,36; Q3)<\/p>\n\n\n\n Hendrikx T, Duan Y, Wang Y, Oh J-H, Alexander L M, Huang W, Emond P, Sokol H, Van Pijkeren J P, Schnabl B. Bacteria Engineered to Produce IL22 in Intestine Induce Expression of REG3G to Reduce Ethanol-induced Liver Disease in Mice. Gut 2019 68, 8, 1504-1515<\/a>. <\/p>\n\n\n\n Lefevre A, Mavel S, Nadal-Desbarats L, Galineau L, Attucci S, Dufour D, Sokol H, Emond P. Validation of global quantitative analysis of tryptophan metabolites in mice using LC-HRMS. Talanta. 2019 Apr 1;195:593-598.<\/p>\n\n\n\n Beauclercq S, Lefevre A, Montigny F, Collin A, Tesseraud S, Leterrier C, Emond P, Guilloteau L. A multiplatform metabolomic approach to characterize fecal signatures of negative postnatal events in chicks: a pilot study. Journal of Animal Science and Biotechnology. 2019 Apr 9;10:21 <\/p>\n\n\n\n 2018<\/p>\n\n\n\n Madji Hounoum B, Blasco H, Coqie E, Vourc\u2019h P, Emond P, Corcia P, Andres C, Raoul C, Mavel S. The Metabolic Disturbances Of Motoneurons Exposed To Glutamate. Mol Neurobiol 2018, 55, 7669-76 Doi: 10.1007\/S12035-018-0945-8. <\/p>\n\n\n\n Mavel S, Lefevre A, Bakhos D, Dufour D, Blasco H, Emond P. Validation Of Metabolomics Analysis Of Human Perilymph Fluid Using Liquid Chromatography-Mass Spectroscopy Hear Res 2018, 367, 129-136 doi: 10.1016\/j.heares.2018.05.016<\/p>\n\n\n\n Bitar T, Mavel S, Emond P, Nadal-Desbarats L, Lefevre A, Mattar H, Soufia M, Blasco H, Vourc\u2019h P, Hleihel W, Andres C. Identification Of Metabolic Pathway Disturbances Using Multimodalmetabolomics In Autistic Disorders In A Middle Eastern Population; J Pharm Biomed Anal 2018, 152, 57-65 <\/p>\n\n\n\n Bruno C, Patin F, Bocca C, Nadal-Desbarats L, Bonnier F, Reynier P, Emond P, Vourc\u2019h P, Joseph-Delafont K, Corcia P, Andres C, Blasco H. The Combinaison Of Four Analytical Methods To Explore Skeletal Muscle Metabolomics: Better Coverage Of Metabolic Pathways Or A Marketing Argument? J Pharm Biomed Anal 2018, 148, 273-279 <\/p>\n\n\n\n Miani M, Le Naour J, Waeckel-Enee E, Verma Sc, Straube M, Emond P, Ryffel B, Van Endert P, Sokol H, Diana J. Gut Microbiota-Stimulated Innate Lymphoid Cells Support \u0392-Defensin 14 Expression In Pancreatic Endocrine Cells, Preventing Autoimmune Diabetes. Cell Metab.<\/a> 2018 Oct 2;28(4):557-572 <\/p>\n\n\n\n Beauclercq S, Nadal-Desbarats L, Hennequet-Antier C, Gabriel I, Tesseraud S, Calenge F, Le Bihan-Duval E, Mignon-Grasteau S. Relationships Between Digestive Efficiency And Metabolomic Profiles Of Serum And Intestinal Contents In Chickens. Sci Rep. 2018 Apr 27;8(1):6678<\/p>\n\n\n\n 2017<\/p>\n\n\n\n Foucault-Fruchard L, Domene A, Page G, Windsor M, Emond P, Rodrigues N, Dolle F, Damont A, Buron F, Routier S, Chalon S, Antier D. Neuroprotective Effect Of The Alpha 7 Nicotinic Receptor Agonist Pha 543613 In An In Vivo Excitotoxic Adult Rat Model. Neuroscience 2017, 356, 52-63 <\/p>\n\n\n\n Dieme B, Lefevre A, Nadal-Desbarats L, Galineau L, Madji-Hounoum B, Montigny F, Blasco H, Andres CR, Emond P, Mavel S. Workflow Methodology For Rat Brain Metabolome Exploration Using Nmr, Lc-Ms And Gc-Ms Analytical Platforms. J Pharm Biomed Anal. 2017 , 142, 270-278 <\/p>\n\n\n\n Madji Hounoum B, Mavel S, Coque E, Patin F, Vourc\u2019h P, Marouillat S, Nadal-Desbarats L, Emond P, Corcia P, Andres C, Raoul C, Blasco H. Wildtype Motoneurons, Als-Linked Sod1 Mutation And Glutamate Profoundly Modify Astrocyte Metabolism And Lactate Shuttling. Glia 2017 ,65(4), 592-605 I<\/p>\n\n\n\n Veyrat-Durebex C, Corcia P, Piver E, Devos D, Dangoumeau A, Gouel F, Vourc\u2019h P, Emond P, Laumonier F, Nadal-Desbarats L, Gordon PH, Andres C, Blasco H. Disruption Of Tca Cycle And Glutamate Metabolism Identified By Metabolomics In An In Vitro Model Of Amyotrophic Lateral Sclerosis. Molecular Neurobiology 2017 Volume: 53, Issue: 10, Pages: 6910-6924<\/p>\n\n\n\n Muhrez K, Nadal-Desbarats L, Halimi JM, Dieme B, Buhler M, Emond P, Blasco H, Le Guellec C. Elucidating Time-Dependent Changes In The Urinary Metabolome Of Renal Transplant Patients By A Combined H-1 Nmr And Gc-Ms Approach. Molecular Biosystems 2017 Volume: 13, Issue: 2, Pages: 432-432<\/p>\n\n\n\n Veyrat-Durebex C, Debeissat C, Blasco H, Patin F, Henique H, Emond P, Antar C, Gissot V, Herault O, Maillot F. Hyperphenylalaninemia Correlated With Global Decrease Of Antioxidant Genes Expression In White Blood Cells Of Adult Patients With Phenylketonuria. Jimd Rep. 2017.<\/p>\n\n\n\n Muhrez K, Largeau B, Emond P, Montigny F, Halimi JM, Trouillas P, Barin-Leguellec C. Single Nucleotide Polymorphisms Of Abcc2 Modulate Renal Secretion Of Endogenous Organic Anions. Biochem Pharmacol. 2017, 140, 124-138 <\/p>\n\n\n\n Vayne C, Deroche L, Drilled N, Patin F, Bruno C, Maillot F, Labarthe F, Corcia P, Benz De Bretagne I, Andres C, Emond P, Blasco H. An Uplc-Msms Method To Measure Plasma Homocysteine Concentration. Ann Biol Clin (Paris) 2017, 75(3), 334-338 <\/p>\n\n\n\n Muhrez K, Nadal-Desbarats L, Halimi Jm, Dieme B, Buhler M, Emond P, Blasco H, Le Guellec C. Elucidating time-dependent changes in the urinary metabolome of renal transplant patients by a combined H-1 NMR and GC-MS approach. Molecular Biosystems 2017 Volume: 13, Issue: 2, Pages: 432-432<\/p>\n\n\n\n Veyrat-Durebex C, Debeissat C, Blasco H, Patin F, Henique H, Emond P, Antar C, Gissot V, Herault O, Maillot F. Hyperphenylalaninemia Correlated with Global Decrease of Antioxidant Genes Expression in White Blood Cells of Adult Patients with Phenylketonuria. JIMD Rep. 2017.<\/p>\n\n\n\n 2016<\/p>\n\n\n\n Madji Hounoum B, Blasco H, Emond P, Mavel S. Liquid Chromatography-High Resolution Mass Spectrometry-Based Cell Metabolomics: Experimental Design, Recommendations And Applications. Trac Trends In Analytical Chemistry 2016, 75, 118-128 <\/p>\n\n\n\n Madji Hounoum B, Vourc\u2019h P, Romain F, Corcia P, Patin F, Gueguinou M, Potier-Cartereau M, Vandier C, Raoul C, Andres C R, Mavel S, Blasco H. NSC-34 motor neuron-like cells are unsuitable as experimental model for glutamate-mediated excitotoxicity. Front Cell Neurosci, 2016, 10, 118 doi: 10.3389\/fncel.2016.00118.<\/p>\n\n\n\n Blasco H, Nadal-Desbarats L, Pradat PF, Gordon PH, Madji-Hounoum B, Patin F, Veyrat-Durebex C, Mavel S, Beltran S, Emond P, Andres CA, Corcia P. Biomarkers In Amyotrophic Lateral Sclerosis: Combining Metabolomic And Clinical Parameters To Define Disease Progression. Eur. J. Neurology 2016, 23(2),346-53 <\/p>\n\n\n\n Bruno C, Dufour-Rainfray D, Patin F, Vourc\u2019h P, Guilloteau D, Maillot F, Labarthe F, Tardieu M, Andres CA, Emond P, Blasco H. Validation Of Amino-Acids Measurement In Dried Blood Spot By Fia-Ms\/Ms For Pku Management. Clin Biochem. 2016 49, 13-14, 1047-50 <\/p>\n\n\n\n Blasco H, Veyrat-Durebex C, Bertrand M, Patin F, Labarthe F, Henique H, Emond P, Andres CA, Antar C, Landon C, Nadal-Desbarats L, Maillot F. A Multiplatform Metabolomics Approach To Characterize Plasma Levels Of Phenylalanine And Tyrosine In Phenylketonuria. Jimd Report 2016, 1-11 <\/p>\n\n\n\n Muhrez K, Benz De Bretagne I, Nadal-Desbarats L, Blasco H, Gyan E, Choquet S, Montigny F, Emond P, Barin-Le Guellec C; Endogenous Metabolites That Are Substrates Of Organic Anion Transporter’s (Oats) Predict Methotrexate Clearance. Pharmacol Res. 2016, June<\/p>\n\n\n\n Fermier B, Blasco H, Godat E, Bocca C, Moenne J, Emond P, Andres C, Laffon M, Ferrandiere M. Specific Metabolome Profile O Exhaled Breath Condensate In Patients With Shock And Respiratory Failure: A Pilot Study. Metabolites 2016, 6(1).<\/p>\n\n\n\n Blasco H, Nadal-Desbarats L, Pradat Pf, Gordon Ph, Madji-Hounoum B, Patin F, Veyrat-Durebex C, Mavel S, Beltran S, Emond P, Andres Ca, Corcia P. Biomarkers in amyotrophic lateral sclerosis: combining metabolomic and clinical parameters to define disease progression. Eur. J. Neurology 2016, 23(2),346-53<\/p>\n\n\n\n Dieme B, Mavel S, Blasco H, Tripi G, Bonnet-Brilhault F, Malvy J, Bocca C, Andres C, Nadal-Desbarats L, Emond P. Metabolomics study of urine in autism spectrum disorders using a multiplatform analytical methodology. J. Prot.Res. 2015 14(12):5273-82<\/p>\n\n\n\n Bruno C, Dufour-Rainfray D, Patin F, Vourc\u2019h P, Guilloteau D, Maillot F, Labarthe F, Tardieu M, Andres Ca, Emond P, Blasco H. Validation of amino-acids measurement in dried blood spot by FIA-MS\/MS for PKU management. Clin Biochem. 2016 49, 13-14, 1047-50<\/p>\n","protected":false},"excerpt":{"rendered":" 2023 Kouno T, Zeng S, Wang Y, Duan Y, Lang S, Gao B, Hartmann P, Cabr\u00e9 N, Llorente C, Galbert C, Emond P, Sokol H, James M, Chao CC, Gao JR, Perreault M, Hava DL, Schnabl B. Engineered bacteria producing aryl-hydrocarbon receptor agonists protect against ethanol-induced liver disease in mice. Alcohol Clin Exp Res. 2023 … Continuer la lecture de « Publications »<\/span><\/a><\/p>\n","protected":false},"author":5,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"_links":{"self":[{"href":"https:\/\/metabolomique.med.univ-tours.fr\/index.php?rest_route=\/wp\/v2\/pages\/112"}],"collection":[{"href":"https:\/\/metabolomique.med.univ-tours.fr\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/metabolomique.med.univ-tours.fr\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/metabolomique.med.univ-tours.fr\/index.php?rest_route=\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/metabolomique.med.univ-tours.fr\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=112"}],"version-history":[{"count":7,"href":"https:\/\/metabolomique.med.univ-tours.fr\/index.php?rest_route=\/wp\/v2\/pages\/112\/revisions"}],"predecessor-version":[{"id":210,"href":"https:\/\/metabolomique.med.univ-tours.fr\/index.php?rest_route=\/wp\/v2\/pages\/112\/revisions\/210"}],"wp:attachment":[{"href":"https:\/\/metabolomique.med.univ-tours.fr\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=112"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}